Article

Machine Learning-Driven Probability Scoring Enhances Diagnostic Certainty and Reduces Costs in Suspected Periprosthetic Joint Infection

2026-02-13

Abstract excerpt

<h4>Background: </h4> Accurate diagnosis of periprosthetic joint infection (PJI) remains challenging, particularly in culture-negative and borderline cases where current practices lead to high diagnostic uncertainty. SynTuition™, a machine-learning–based probability score integrating preoperative biomarkers, was developed to support clinical decision-making. This study compared its diagnostic performance and econo...

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Literature Corpus work: 59bb9f58-8070-5f48-add6-6f78af985e4d
DOI: 10.20944/preprints202601.1339.v2

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