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Transformers Achieve 4× Better Cross-Scanner Generalization Than CNNs: Multi-Center Validation of 3D Swin Transformers Across 1,066 Subjects

2026-07-02

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<title>Abstract</title> <p>Purpose: Cross-scanner generalization remains the critical barrier to clinical deployment of deep learning for medical image segmentation [1], [2]. While convolutional neural networks (CNNs) show 8-15% performance degradation when applied to data from different scanners [3]–[5], the ability of transformer architectures [6], [7] to learn scanner-invariant features is unknown. This work p...

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Literature Corpus work
59a27830-a2c0-51c8-ae04-a56e4fe086b1
DOI
10.21203/rs.3.rs-9402599/v1
Open publication

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Transformers Achieve 4× Better Cross-Scanner Generalization Than CNNs: Multi-Center Validation of 3D Swin Transformers Across 1,066 SubjectsDOI 10.21203/rs.3.rs-9402599/v1
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