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Pan-cancer analysis of DNMT3A as a robust prognostic biomarker to predict the immunotherapy response

2023-07-31

Abstract excerpt

<h4>Background: </h4> DNA methyltransferase 3A (DNMT3A) is essential for de-novo methylation and cell development. Recent studies have shown that dysregulation of methylation regulated by DNMT3A is highly implicated in cancer progression. However, the regulatory roles of DNMT3A in various cancers are not completely clear and need further investigation. Methods The RNA-seq data in The Cancer Genome Atlas (TCGA) an...

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Literature Corpus work
587dc48c-fdad-5f0f-b774-63d078597b3e
DOI
10.21203/rs.3.rs-3149495/v1
Open publication

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