Article

DeepDRIM: a deep neural network to reconstruct cell-type-specific gene regulatory network using single-cell RNA-Seq Data

2021-02-03

Abstract excerpt

<h4> A bstract </h4> Single-cell RNA sequencing is used to capture cell-specific gene expression, thus allowing reconstruction of gene regulatory networks. The existing algorithms struggle to deal with dropouts and cellular heterogeneity, and commonly require pseudotime-ordered cells. Here, we describe DeepDRIM a supervised deep neural network that represents gene pair joint expression as images and considers t...

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Literature Corpus work: 584143d1-6b47-555d-9071-2a2904f6c946
DOI: 10.1101/2021.02.03.429484

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