Article

Aberrant expression prediction across human tissues

2023-12-04

Abstract excerpt

Despite the frequent implication of aberrant gene expression in diseases, algorithms predicting aberrantly expressed genes of an individual are lacking. To address this need, we compiled an aberrant expression prediction benchmark covering 8.2 million rare variants from 633 individuals across 48 tissues. While not geared toward aberrant expression, the deleteriousness score CADD and the loss-of-function predictor...

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Literature Corpus work: 5585e3b8-5151-56b5-8718-e7dccb8b3a5c
DOI: 10.1101/2023.12.04.569414

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