Article

Rate of protein synthesis is reduced in peripheral blood mononuclear cells (PBMCs) from Fragile X individuals

2020-09-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Fragile X syndrome (FXS) is the leading inherited cause of intellectual disability and is caused by the loss of expression of the Fragile X mental retardation protein (FMRP). In animal model of FXS, the absence of FMRP leads to an aberrant rate of neuronal protein synthesis, which in turn is believed to be at the origin of defects regarding spine morphology and...

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Literature Corpus work: 54285ad5-be8f-567d-b025-de75ed1704b5
DOI: 10.21203/rs.3.rs-63987/v1

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