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Identification And Validation of A Cigarette Smoke-Related Five-Gene Signature As A Prognostic Biomarker In Kidney Renal Clear Cell Carcinoma

2021-07-01

Abstract excerpt

Cigarette smoking greatly promotes the progression of kidney renal clear cell carcinoma (KIRC), however, the underlying molecular events has not been fully established. In this study, RCC cells were exposed to the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK, nicotine-derived nitrosamine ketone) for 120 days, and then the soft agar colony formation, wound healing and transwell a...

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Literature Corpus work
53c6fce9-a008-5136-b7d6-c923613fa082
DOI
10.21203/rs.3.rs-593776/v1
Open publication

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