A malignant epithelioid tumor with EWSR1 fusion mimics primary pulmonary myxoid sarcoma (PPMS): a variant of PPMS or under-recognized entity?

Abstract excerpt

<title>Abstract</title> <p>Background Primary pulmonary myxoid sarcoma (PPMS) is an extremely rare soft tissue tumor that is characterized in most cases by the oncogenic fusion gene <italic>EWSR1-CREB1</italic>. Tumor cells with epithelioid differentiation have not been described in PPMS. We report a primary lung tumor with morphological, immunohistochemical and molecular features closely mimics PPMS, but with c...

Topics

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• Calmodulin-Binding Proteins
• Cyclic AMP Response Element-Binding Protein
• Disease-Free Survival
• Gene Fusion
• Gene Rearrangement
• RNA-Binding Protein EWS
• RNA-Binding Proteins
• Sarcoma

Identifiers and source

Literature Corpus work

52e0a4f4-0943-5c00-abf2-c3fa0c2d6a3f

DOI

10.21203/rs.3.rs-4488939/v1