Article

Identification of novel key biomarkers in Simpson-Golabi-Behmel Syndrome: Evidence from bioinformatics analysis

2019-04-14

Abstract excerpt

<h4>Background</h4> The Simpson-Golabi-Behmel Syndrome (SGBS) or overgrowth Syndrome is a rare inherited X-linked condition characterized by pre- and postnatal overgrowth. The aim of the present study is to identify functional non-synonymous SNPs of GPC3 gene using various in silico approaches. These SNPs are supposed to have a direct effect on protein stability through conformation changes. <h4>Material and meth...

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Literature Corpus work: 51483a3d-68d2-53d8-9346-0255e53d831d
DOI: 10.1101/608927

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