Constructing Causal Pathways for Premature Cardiovascular Disease Mortality using Directed Acyclic Graphs: Integrating Evidence Synthesis and Expert Knowledge

Abstract excerpt

<title>Abstract</title> <p>Cardiovascular disease (CVD) is a major global cause of premature mortality. While multiple studies propose CVD mortality prediction models based on regression frameworks, incorporating causal understanding through causal inference approaches can enhance accuracy. This paper demonstrates a methodology combining evidence synthesis and expert knowledge to construct a causal model for prem...

Topics

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• Algorithms
• Cardiovascular Diseases
• Genomics
• Medical Informatics
• Models, Statistical
• Polymorphism, Single Nucleotide
• Principal Component Analysis
• Risk Factors

Identifiers and source

Literature Corpus work

505eadf0-01f8-5d91-8b2e-e4c3fb3f6961

DOI

10.21203/rs.3.rs-4308893/v1