Article

Genomic Compute Trifecta

2025-07-04

Abstract excerpt

In this paper, we present the Genomic Compute Trifecta, which are the fundamental structural barriers to scalable computation of genomics and multi-omics workloads due to the complexity of the data structure and its incompatibility with the assumptions underpinning traditional computing architectures. Bioinformatics pipelines work over sparse graphs with nonuniform memory access patterns, dynamic control flow, and...

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Literature Corpus work: 4ca98e3e-b0ff-5883-9ea1-31ea69c10ed4
DOI: 10.20944/preprints202507.0357.v1

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