Article

Novel Use of Siltuximab in a Patient with Somatic UBA1 Mutated VEXAS Syndrome

2024-10-16

Abstract excerpt

<title>Abstract</title> <p>VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is an increasingly recognized disorder that occurs due to somatic mutations of a ubiquitin-activating enzyme encoded by ubiquitin-like modifier activating enzyme 1 gene, <italic>UBA1</italic>. Clinical findings associated with VEXAS syndrome include recurrent fevers, polychondritis, periorbital edema, pleural effu...

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Literature Corpus work: 4c5344b8-b53c-55c3-89b4-b606d73a6f1b
DOI: 10.21203/rs.3.rs-4952720/v1

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