Article

Urinary peptidomic signatures predict overall and progression-free survival in patients with bladder cancer

2025-10-29

Abstract excerpt

Clinicopathologic calculators for bladder cancer moderately predict survival and fail to depict the underlying molecular phenotype. We applied urinary capillary electrophoresis–mass spectrometry (CE–MS) to identify prognostic signatures linked to bladder cancer outcome. In a discovery cohort (n=131; mean follow-up 623 days), 114 survival-associated peptides, predominantly collagen fragments, were significant progn...

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Literature Corpus work: 4b410d52-b0c9-5821-aa38-ffc365f80b5f
DOI: 10.1101/2025.10.28.25338944

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