Article

iPSC-Derived Myogenic Progenitor Cells from People with ME/CFS Reveal Altered Genes and Pathways with Drug Repurposing Potential

2026-07-21

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating multisystem disorder characterised by profound fatigue, post-exertional malaise, muscle pain and weakness. Although skeletal muscle abnormalities and mitochondrial alterations have been reported in people with ME/CFS, the underlying biological processes remain poorly understood, and...

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Literature Corpus work: 4a5e0dd5-e755-525f-9120-889ce070cea8
DOI: 10.21203/rs.3.rs-10015511/v2

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