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AI-Driven Fluorescence Peak Analysis for Chromosomal Aneuploidy Detection: A Python-Based Machine Learning Approach for Enhanced Accuracy and Efficiency

2025-03-24

Abstract excerpt

Chromosomal aneuploidy, a condition characterized by an abnormal number of chromosomes, is a major genetic disorder affecting human reproduction, leading to infertility, pregnancy loss, and developmental disabilities. Trisomies of chromosomes 13, 18, and 21 result in Patau, Edwards, and Down syndromes, respectively. While conventional methods like karyotyping and QF-PCR facilitate aneuploidy detection, they are of...

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Literature Corpus work: 497fcb46-aec0-5c3a-a447-bf2b2ab35397
DOI: 10.1101/2025.03.22.25324455

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