Article

3D finite element models reveal regional fatty infiltration modulates tibialis anterior force generating capacity in FSHD

2025-02-20

Abstract excerpt

Facioscapulohumeral muscular dystrophy (FSHD) is a progressive neuromuscular disorder characterized by muscle damage, fibro-fatty infiltration, and ultimately weakness. The tibialis anterior (TA), very often involved relatively early in FSHD, is a primary dorsiflexor and important for ambulation. Recent work using magnetic resonance imaging to quantify fat infiltration in the TA volume observed a steep decline in...

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Literature Corpus work: 47bff42c-a2a1-5f43-8f5c-61573238d9c0
DOI: 10.1101/2025.02.15.25322140

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