Back to search

Article

Topological gene-expression networks recapitulate brain anatomy and function

2018-11-25

Abstract excerpt

Understanding how gene expression translates to and affects human behaviour is one of the ultimate aims of neuroscience. In this paper, we present a pipeline based on Mapper, a topological simplification tool, to produce and analyze genes co-expression data. We first validate the method by reproducing key results from the literature on the Allen Human Brain Atlas, and the correlations between resting-state fMRI an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
47b89133-9e61-5006-90f9-9e8e418398f1
DOI
10.1101/476382
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Topological gene-expression networks recapitulate brain anatomy and functionDOI 10.1101/476382
Select a neighboring publication to make it the new centre.