Article

Identification of Long Non-coding RNA Candidate Disease Genes Associated with Clinically Reported CNVs in Congenital Heart Disease

2024-10-02

Abstract excerpt

<h4> A bstract </h4> <h4>Background</h4> Copy Number Variants ( CNVs ) contribute to 3-10% of isolated Congenital Heart Disease ( CHD ) cases, but their roles in disease pathogenesis are often unclear. Traditionally, diagnostics have focused on protein-coding genes, overlooking the pathogenic potential of non-coding regions constituting 99% of the genome. Long non-coding RNAs ( lncRNAs ) are increasingly re...

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Literature Corpus work: 456f89c3-5321-5147-8a0f-10dac8bb2ecf
DOI: 10.1101/2024.09.30.615967

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