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miR-124-3p and miR-181a-5p Mediate AT1-Receptor Autoantibody Induced Fetal Rat Cardiac Remodeling via Increased VCAN Expression

2022-03-11

Abstract excerpt

<title>Abstract</title> <p>Autoantibodies against angiotensin II type 1 receptor (AT1-AA) are prevalent in preeclampsia. They induce fetal cardiac structural remodeling in late pregnancy via still unknown mechanisms, the subject of this study’s investigation. MicroRNA array revealed differential expression of microRNAs in fetal hearts exposed to AT1-AA. miR-124-3p and miR-181a-5p, the most significantly altered m...

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Literature Corpus work
456b4e03-a1d2-5a14-af89-6f5bcd850de1
DOI
10.21203/rs.3.rs-1430465/v1
Open publication

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miR-124-3p and miR-181a-5p Mediate AT1-Receptor Autoantibody Induced Fetal Rat Cardiac Remodeling via Increased VCAN ExpressionDOI 10.21203/rs.3.rs-1430465/v1
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