Article

Oncolytic Virotherapy Combined with Nivolumab Elicits Complete Responses in Muscle-Invasive Bladder Cancer in Association with the Formation of Tertiary Lymphoid Structures

2024-01-18

Abstract excerpt

<title>Abstract</title> <p>There is a critical unmet need for safe and efficacious neoadjuvant treatment for cisplatin-ineligible patients with muscle invasive bladder cancer. We launched a Phase 1b study using the combination of intravesical cretostimogene grenadenorepvec (oncolytic serotype 5 adenovirus encoding granulocyte-macrophage colony stimulating factor) with systemic nivolumab in cisplatin-ineligible pa...

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Literature Corpus work: 44a92c2e-8542-5b0f-8540-faa2d252d052
DOI: 10.21203/rs.3.rs-3864301/v1

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