Article

Still Not Sterile: Chlorhexidine gluconate treatment does not completely reduce skin microbial bioburden and promotes pathogen overabundance in patients undergoing elective surgeries

2024-07-21

Abstract excerpt

Surgical site infections (SSI) continue to occur despite widespread adoption of surgical antiseptics. The effects of chlorhexidine gluconate (CHG)-based antiseptics on the skin microbiome also remains undefined due to confounding effects of CHG persistence on skin. Patients undergoing elective surgery were enrolled to characterize the immediate and long-term impact of pre-surgical preparation with CHG antiseptic o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 441969e5-ee90-59ca-af52-5e9c3137dd5a
DOI: 10.1101/2024.07.20.602341

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Still Not Sterile: Chlorhexidine gluconate treatment does not completely reduce skin microbial bioburden and promotes pathogen overabundance in patients undergoing elective surgeriesDOI 10.1101/2024.07.20.602341Read

Establishing an ex vivo porcine skin model to investigate the effects of broad spectrum antiseptic on viable skin microbial communitiesSemantic proximity Read

Respect of Skin Microbiome with Different Types of LeavE-on Skincare Products, an Ecobiological ApproachSemantic proximity Read

A Comprehensive Analysis of Antimicrobial Agents Used in Surgical Prophylaxis in Clean Case: A ReviewSemantic proximity Read

Minimizing Surgical-Site InfectionsSemantic proximity Read

Time-dependent displacement of commensal skin microbes by pathogens at the site of colorectal surgerySemantic proximity Read

General Skin and Nasal Decolonization with octenisan® Set before and after Elective Orthopedic Surgery in Selected Patients at Elevated Risk for Revision Surgery and Surgical Site Infections - A Single-Center, Unblinded, Superiority, Randomized-Controlled Trial (BALGDEC Trial)Semantic proximity Read

Selective Depletion of Staphylococcus aureus Restores the Skin Microbiome and Accelerates Tissue Repair after InjurySemantic proximity Read

Recent advances in single-cell engineered live biotherapeutic products research for skin repair and disease treatmentSemantic proximity Read

The potential prebiotic effect of 2‐Butyloctanol on the human axillary microbiomeSemantic proximity Read

Bacterial DNA on the skin surface overrepresents the viable skin microbiomeSemantic proximity Read

Chemical Bowel Preparation Exerts an Independent Preventive Effect Against Surgical Site Infection Following Elective Laparoscopic Colorectal SurgerySemantic proximity Read

Treatment of Axillary Osmidrosis by Rebalancing Skin Microecology With Lactobacillus bulgaricusSemantic proximity Read