Mapping the Hidden Secretome in Leishmania Parasites Using a Proteogenomics Approach

Abstract excerpt

<title>Abstract</title> <p> <bold>Introduction</bold> Leishmaniasis affects millions of people worldwide and is caused by obligate intracellular protozoan parasites transmitted through infected phlebotomine sand flies. Clinical outcomes range from self-healing cutaneous lesions to fatal visceral disease across twenty recognised human-pathogenic species. Although <italic>Leishmania</italic> genomes are remarka...

Topics

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• Enzyme Production and Characterization
• Extracellular vesicles in disease
• Insect Pest Control Strategies
• Parasites and Host Interactions
• Research on Leishmaniasis Studies
• Trypanosoma species research and implications
• vaccines and immunoinformatics approaches
• Viral Infectious Diseases and Gene Expression in Insects

Identifiers and source

Literature Corpus work

440a918c-dfc4-561d-b79f-1c59bedcb379

DOI

10.21203/rs.3.rs-8472209/v1