Back to search

Article

Transcriptome-based cell type assignment for kidney cell culture models

2026-04-01

Abstract excerpt

<h4>Background</h4> Kidney cell lines are widely used to model kidney physiology and disease; however, their gene expression profiles may differ from primary cells due to immortalization, culture conditions, or experimental treatments. Determining whether a cell line resembles its native cell type is critical for interpreting in vitro findings. We developed a transcriptome-based approach that matches bulk RNA-seq...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
43837430-0e19-5a53-81f7-ea726f20da39
DOI
10.64898/2026.03.30.715265
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Transcriptome-based cell type assignment for kidney cell culture modelsDOI 10.64898/2026.03.30.715265
Renal-Tubule Epithelial Cell Nomenclature for Single-Cell RNA-Sequencing StudiesSemantic proximity
An Integrated Atlas of the Human Kidney Spanning Health and DiseasesSemantic proximity
Novel Human Kidney Cell Subsets Identified by Mux-SeqSemantic proximity
Integrated Single-Cell Transcriptomic Atlas of Human Kidney Endothelial CellsSemantic proximity
Urinary single-cell sequencing captures intrarenal injury and repair processes in human acute kidney injurySemantic proximity
A reference tissue atlas for the human kidneySemantic proximity
Transcriptomes of Major Proximal Tubule Cell Culture ModelsSemantic proximity
Systematic evaluation of single-cell multimodal data integration enhances cell type resolution and discovery of clinically relevant states in complex tissuesSemantic proximity
Guided construction of single cell reference for human and mouse lungSemantic proximity
Validation of the Nanostring of the Banff Human Organ Transplant Gene Panel in Archival Data from Human Kidney Transplants and its Modelling ComplexitySemantic proximity
A reference tissue atlas for the human kidneySemantic proximity
Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy responseSemantic proximity
Select a neighboring publication to make it the new centre.