LncRNA miR663AHG represses the development of colon cancer in a miR663a expression-dependent negative feedback loop

Abstract excerpt

<title>Abstract</title> <p>Background The <italic>MIR663AHG</italic> gene encode both <italic>miR663AHG</italic> and <italic>miR663a</italic>. While <italic>miR663a</italic> contributes to the defense of host cells against inflammation and inhibits colon cancer development, the biological function of lncRNA <italic>miR663AHG</italic> has not been previously reported. Methods The subcellular localization of lncR...

Topics

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• Cancer Mechanisms and Therapy
• Cancer-related molecular mechanisms research
• CRISPR and Genetic Engineering
• MicroRNA in disease regulation
• Mycobacterium research and diagnosis
• Peptidase Inhibition and Analysis
• RNA and protein synthesis mechanisms
• RNA modifications and cancer

Identifiers and source

Literature Corpus work

42253217-19cf-5882-9358-7035fb21fa2d

DOI

10.21203/rs.3.rs-1948902/v1