Article
Networks and genes modulated by posterior hypothalamic stimulation in patients with aggressive behaviours: Analysis of probabilistic mapping, normative connectomics, and atlas-derived transcriptomics of the largest international multi-centre dataset
2022-11-01
Abstract excerpt
<h4>ABSTRACT</h4> Deep brain stimulation targeting the posterior hypothalamus (pHyp-DBS) is being investigated as treatment for refractory aggressive behaviour, but its mechanisms of action remain elusive. We conducted an integrated imaging analysis of a large multi-centre dataset, incorporating volume of activated tissue modeling, probabilistic mapping, normative connectomics, and atlas-derived transcriptomics....
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Identifiers and source
- Literature Corpus work
- 3ee6c79e-9122-5c9d-9978-43c86b5e5afe
- DOI
- 10.1101/2022.10.29.22281666
