Article

A case of novel NFKB2 mutation with hypertensive emergency and nephrotic syndrome leading to CKD G5D

2023-12-21

Abstract excerpt

<title>Abstract</title> <p>[Background] Nuclear factor kappa B (NF-κB) family plays a central role in human immune system regulation. Heterozygous mutations in <italic>NFKB2</italic> typically cause immunodeficiency with various degrees of central adrenal insufficiency, autoimmunity and ectodermal dysplasia. No reported case has presented kidney failure as an initial symptom. Moreover, documentation of kidney inv...

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Literature Corpus work: 3c7936db-68b8-5338-96d2-31e0259fdb5d
DOI: 10.21203/rs.3.rs-3768322/v1

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