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Article

Hypoxia-mimicking bioactive materials for skeletal tissue engineering

2011-01-01

Abstract excerpt

The next generation of regenerative medicine solutions will depend on smart materials that can activate “self-healing” mechanisms. Cells respond to changes in pO2 through a hypoxia-sensing pathway, the HIF-1 pathway, which activates numerous processes necessary for bone and cartilage development and for normal tissue repair. Control of these processes is critical in tissue engineering (TE), therefore this thesis a...

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Literature Corpus work
3a481009-09d9-5ca5-ad81-5039eca164de
DOI
10.25560/9005
Open publication

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Hypoxia-mimicking bioactive materials for skeletal tissue engineeringDOI 10.25560/9005
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