Article

Federated analysis of BRCA1 and BRCA2 variation in a Japanese cohort

2021-06-06

Abstract excerpt

<h4>Summary</h4> More than 40% of the germline variants in ClinVar today are variants of uncertain significance (VUS). These variants remain unclassified in part because the patient-level data needed for their interpretation is siloed. Federated analysis can overcome this problem by “bringing the code to the data”: analyzing the sensitive patient-level data computationally within its secure home institution and p...

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Literature Corpus work: 3a268ee8-9647-5ad6-a162-9ac036186aff
DOI: 10.1101/2021.06.04.447169

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