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Prenatal Exome Sequencing of Fetuses with Central Nervous System Anomalies Based on Prenatal Ultrasound and Magnetic Resonance Imaging Diagnosis — A Retrospective Cohort Study and System Review

2024-12-18

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<title>Abstract</title> <p>Background Assessing the incremental yield of prenatal exome sequencing (ES) over chromosomal microarray analysis (CMA) in the diagnosis of central nervous system (CNS) anomalies based on prenatal ultrasound and magnetic resonance imaging (MRI) diagnoses. Methods In this retrospective cohort study, we collected the ES results of fetuses diagnosed with CNS anomalies through prenatal ul...

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Literature Corpus work: 3960e726-080c-5f61-8956-2bd353342445
DOI: 10.21203/rs.3.rs-5459992/v1

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