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Article

Elucidating the constitutional genetic basis of multiple primary tumours

2019-01-01

Abstract excerpt

Cancer predisposition syndromes are responsible for a significant minority of neoplasm occurrences and beget opportunities to mitigate the associated risks with clinical intervention. They are caused by constitutional genetic variation affecting tumour suppressor genes or proto-oncogenes and recent improvements in sequencing technology have led to greater capability to detect more affected individuals through diag...

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Identifiers and source

Literature Corpus work
37cb155b-cdf0-56ff-a9a7-f17468a1d807
DOI
10.17863/cam.40637
Open publication

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