Article

Inferring the sensitivity of wastewater metagenomic sequencing for early detection of viruses: a statistical modelling study

2023-12-26

Abstract excerpt

<h4>Background</h4> Metagenomic sequencing of wastewater (W-MGS) can in principle detect any known or novel pathogen in a population. We quantify the sensitivity and cost of W-MGS for viral pathogen detection by jointly analysing W-MGS and epidemiological data for a range of human-infecting viruses. <h4>Methods</h4> Sequencing data from four studies were analysed to estimate the relative abundance (RA) of 11 hum...

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Literature Corpus work: 3720f301-d6c0-55a9-87f3-7d37c4905ba9
DOI: 10.1101/2023.12.22.23300450

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