High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients

Abstract excerpt

Pediatric extreme thrombocytosis (EXT, platelet count > 1000 x 103/µL) is rare. In a single center retrospective analysis of hospitalized children with EXT, infants with congenital diaphragmatic hernia (CDH) were overrepresented. In general pediatric patients, EXT is usually secondary to infection or inflammation, but most of the 14 CDH patients with EXT had no identifiable inciting factor. Instead, there was evid...

Topics

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• Hematopoietic Stem Cell Transplantation
• Infant
• Infant, Newborn
• Mutation
• Platelet Transfusion
• Receptors, Thrombopoietin
• Syndrome
• Thrombocytopenia

Identifiers and source

Literature Corpus work

370182f8-f5e0-5383-97cc-f131d320cf48

DOI

10.22541/au.170667256.68178066/v1