Article

Fatty acid auxotrophy as driver of Lactobacillus symbiosis in the female urinary tract

2026-04-24

Abstract excerpt

The female urinary microbiome (FUM) has emerged a promising therapeutic target for recurrent urinary traction infection (rUTI). The FUM is dominated by a phylogenetically coherent group of Lactobacillus species whose metabolic relationship with the host remains poorly understood. Here, we demonstrate that fatty acid (FA) auxotrophy is a universal, conserved trait of FUM Lactobacillus species, mechanistically und...

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Literature Corpus work: 361c8ea6-6934-518c-90eb-ef6cb3fb847d
DOI: 10.64898/2026.04.23.720460

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