Article

Novel ARMC5 mutations in primary bilateral macronodular adrenal hyperplasia: a family report

2024-05-02

Abstract excerpt

<title>Abstract</title> <p>Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of overt Cushing's syndrome (CS), which usually manifests as bilateral macronodular adrenal nodules and varying levels of cortisol secretion. Previous studies have shown that ARMC5 gene belongs to tumor suppressor gene, and its germline variants play a huge role in the occurrence of PBMAH, which may be inherited...

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Literature Corpus work: 3601caee-900e-5a32-8923-5bda761dc224
DOI: 10.21203/rs.3.rs-4320615/v1

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