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Isothermal Real-Time RT-RPA for Machupo Virus Detection: Field-Adaptable Sensitivity Comparable with Laboratory PCR

2025-08-26

Abstract excerpt

Isothermal nucleic acid amplification methods, such as recombinase polymerase amplification (RPA), are becoming increasingly vital as diagnostic platforms for neglected tropical diseases (NTDs) by enabling rapid and accurate detection in under-resourced regions. Wse developed a real-time RT-RPA assay for Machupo virus (MACV), the causative agent of Bolivian hemorrhagic fever, and directly compared it to a real-tim...

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Literature Corpus work
35d7d6f1-5888-517e-91c2-d15143b935ec
DOI
10.1101/2025.08.22.25334221
Open publication

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Isothermal Real-Time RT-RPA for Machupo Virus Detection: Field-Adaptable Sensitivity Comparable with Laboratory PCRDOI 10.1101/2025.08.22.25334221
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