Article

Identifying ancient antibiotic resistance genes in archaeological dental calculus

2024-09-23

Abstract excerpt

Research on ancient antimicrobial resistance is limited, and appropriate screening criteria for identifying antibiotic (ARGs) and metal resistance genes (MRGs) in archaeological samples are unclear. We assessed the impact of DNA damage and contamination on ARG and MRG detection in ancient metagenomic sequences. Starting from a set of modern oral metagenomic samples, we simulated diagenetic DNA damage as expected i...

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Literature Corpus work: 34eb9a60-de8d-507e-8eec-e5908378e245
DOI: 10.1101/2024.09.23.614435

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