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Distinct gut virome profiles are associated with response to anti-PD-1 therapy in non-small cell lung cancer

2025-12-15

Abstract excerpt

<title>Abstract</title> <p> Background The gut microbiota plays a critical role in modulating the efficacy of immune checkpoint inhibitor (ICI), yet the contribution of the gut virome remains under-characterized, particularly in advanced non-small cell lung cancer (NSCLC). This study aimed to characterize the gut virome and elucidate its mechanistic involvement in response to PD-1 inhibitor therapy. Methods We p...

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Literature Corpus work
34128608-2467-5d2f-a9e2-bdd3d10469e5
DOI
10.21203/rs.3.rs-8256866/v1
Open publication

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Distinct gut virome profiles are associated with response to anti-PD-1 therapy in non-small cell lung cancerDOI 10.21203/rs.3.rs-8256866/v1
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