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Pre-HCT Resistome Disruption Predicts ESBL Gene Expansion in Pediatric Transplant Recipients: A Prospective Multi-Center Study

2026-01-22

Abstract excerpt

<h4>Background</h4> Infections are the leading cause of non-relapse mortality in pediatric hematopoietic cell transplant (HCT) recipients. Up to 90% of bacteremias in these patients originate from gut microbiome organisms. However, selection for resistance genes, such as Extended-spectrum β-lactamase (ESBL), in these patient’s gut microbiomes remains poorly understood. <h4>Methods</h4> Stools were prospectively...

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Literature Corpus work
3362373f-d978-57ee-8437-d0d0cd1b0172
DOI
10.64898/2026.01.20.26344466
Open publication

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Pre-HCT Resistome Disruption Predicts ESBL Gene Expansion in Pediatric Transplant Recipients: A Prospective Multi-Center StudyDOI 10.64898/2026.01.20.26344466
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