Article

Cholesteryl esters and high protein-to-lipid ratios distinguish Non-Vesicular Extracellular Particles from Extracellular Vesicles

2025-07-03

Abstract excerpt

Extracellular vesicles (EVs) are central to intercellular communication, yet the mechanisms underlying their biogenesis and diversity remain incompletely understood. Here, we integrate meta-analysis, advanced lipidomic, protein-to-lipid profiling, and super-resolution imaging to define the fundamental principles governing EV heterogeneity. Our meta-analysis of published transmission electron microcrographs across...

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Identifiers and source

Literature Corpus work: 335f1494-f66d-530c-8fdf-8965a6a49bfe
DOI: 10.1101/2025.07.01.662358

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