Article

Negativeome in Early-Life Virome Studies: Characterization and Decontamination

2024-10-17

Abstract excerpt

Environmental contamination complicates the study of low-biomass microbial communities like the human gut virome. In 1,321 early-life gut viromes and 55 negative controls (NCs) from four datasets, we identified viral contaminants and their prevalence across studies. Samples and NCs were indistinguishable in genomic and ecological features, with 71.5% of samples sharing at least one identical strain with NCs. This...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 32d06e48-f2b4-5edf-be2b-b75d94000ff6
DOI: 10.1101/2024.10.14.618243

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Negativeome in Early-Life Virome Studies: Characterization and DecontaminationDOI 10.1101/2024.10.14.618243Read

The human gut virome databaseSemantic proximity Read

The human gut virome: composition, colonization, interactions, and impacts on human healthSemantic proximity Read

Emerging view of the human viromeSemantic proximity Read

Illuminating the human virome in health and diseaseSemantic proximity Read

A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseasesSemantic proximity Read

Describing the Silent Human Virome with an Emphasis on Giant VirusesSemantic proximity Read

Beyond cells – The virome in the human holobiontSemantic proximity Read

A Comparison of Methods for the Optimal Recovery of the Human Fecal ViromeSemantic proximity Read

Next Generation Sequencing Approaches to Characterize the Respiratory Tract ViromeSemantic proximity Read

Studying the gut virome in the metagenomic era: challenges and perspectivesSemantic proximity Read

The gut virome: A new microbiome component in health and diseaseSemantic proximity Read

The gut virome: the ‘missing link’ between gut bacteria and host immunity?Semantic proximity Read