Article

Estimate the Frequency of Causal Genetic Variants in Fetuses With Congenital Heart Defects: a Chinese Cohort Study

2021-07-13

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose: </bold>This cohort study was designed to assess the prevalence of chromosomal abnormalities in fetuses with different types of congenital heart defects (CHD).<bold>Methods: </bold>In a cohort of 200 fetuses with CHD, we performed prenatal chromosome microarray analysis (CMA) firstly, and then WES analysis was carried out on some fetuses with negative CMA results. Meanwhil...

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Literature Corpus work: 32b3ba17-9edc-5fe1-8d88-ead4acc1728c
DOI: 10.21203/rs.3.rs-698990/v1

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