Article

The individual and global impact of copy number variants on complex human traits

2021-08-12

Abstract excerpt

<h4>SUMMARY</h4> Copy number variations (CNVs) have been involved in multiple genomic disorders but their impact on complex traits remains understudied. We called CNVs in the UK Biobank and performed genome-wide association scans (GWASs) between the copy-number of CNV-proxy probes and 57 continuous traits, revealing 131 signals spanning 47 phenotypes. Our analysis recapitulated well-known associations (1q21 and he...

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Literature Corpus work: 311a63bf-ca96-5fea-a5ec-d4965c029152
DOI: 10.1101/2021.08.10.21261839

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