Article

Asthma susceptibility in prenatal nicotine-exposed mice attributed to β-catenin increase during CD4+ T cell development.

2024-01-31

Abstract excerpt

<h4>Background: </h4> Asthma, the most frequent allergic airway disease, is related to maternal exposure to cigarette smoke. Our previous studies demonstrated that prenatal exposure to nicotine (PNE), the major active product of smoking, impairs fetal thymopoiesis and CD4+ T cell development after birth. This study aimed to investigate whether PNE contributes to asthma susceptibility through CD4+ T cell developmen...

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Literature Corpus work: 30ebd7b4-6d17-55da-96ed-c2998e667a8f
DOI: 10.22541/au.170666389.90695069/v1

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