Microscopic and Macroscopic Response of a Cortical Neuron to an External Electric Field Computed with the Boundary Element Fast Multipole Method

Abstract excerpt

The goal of this study is to demonstrate how one can compute the activating function and surface charge density resulting from application of an external electric field to a high-resolution realistic neuronal morphology. We use the boundary element fast multipole method (BEM-FMM) on an ordinary computer to accurately perform these computations in under 2-10 minutes for a dense surface mesh of a single neuron with...

Topics

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• Action Potentials
• Data Interpretation, Statistical
• Databases, Factual
• Hippocampus
• Models, Neurological
• Neurons
• Phenotype
• Photoreceptor and optogenetics research

Identifiers and source

Literature Corpus work

3034d6ec-c763-564b-baa2-70b6e2a2ab93

DOI

10.1101/391060