Article

Fast ripples reflect increased excitability that primes epileptiform spikes

2023-03-29

Abstract excerpt

The neuronal circuit disturbances that drive interictal and ictal epileptiform discharges remains elusive. Using a combination of extraoperative macro- and micro-electrode interictal recordings in six presurgical patients during non-rapid eye movement (REM) sleep we found that, exclusively in the seizure onset zone, fast ripples (FR; 200-600Hz), but not ripples (80-200 Hz), frequently occur <300 msec before an int...

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Literature Corpus work: 2e3f1577-409b-5d7b-b46e-ca722149818a
DOI: 10.1101/2023.03.26.23287702

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