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Beyond the Red Complex: <i>De Novo</i> Marker Discovery Uncovers Novel Periodontitis-Associated Taxa and Enables Non-Invasive Machine Learning Diagnosis

2026-08-03

Abstract excerpt

<h4>Background</h4> Periodontitis affects over 1 billion people worldwide, yet diagnosis relies on clinical measures that capture tissue destruction rather than underlying microbial dysbiosis. Most microbial-biomarker studies use 16S rRNA sequencing or reference-database mapping, systematically under-detecting uncultivated or divergent taxa. <h4>Methods</h4> We assembled 341 supra- and subgingival shotgun metage...

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Literature Corpus work: 2e326ed5-babe-5842-8f57-e65d6065af39
DOI: 10.64898/2026.07.31.26359396

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