Article

Identification effective diagnosis biomarkers and immune cell infiltration in liver cancer by bioinformatics analysis and machine learning algorithm

2023-06-06

Abstract excerpt

<h4>Objective: </h4> The aim of this study was to identify the key diagnosis biomarkers of abnormal expression and immune infiltration in liver cancer based on bioinformatics analysis and machine learning algorithm. Methods Three microarray datasets were obtained from Gene Expression Omnibus database, of which GSE88389 and GSE121248 were defined as training sets and GSE45436 was defined as a validation set. Diffe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2e157036-7d25-5b81-b881-041b082da273
DOI: 10.21203/rs.3.rs-2970475/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification effective diagnosis biomarkers and immune cell infiltration in liver cancer by bioinformatics analysis and machine learning algorithmDOI 10.21203/rs.3.rs-2970475/v1Read

Discovery of novel diagnostic biomarkers of hepatocellular carcinoma associated with immune infiltrationSemantic proximity Read

Identification and Analysis of Immune-Related Gene Signature in Hepatocellular CarcinomaSemantic proximity Read

Research into the characteristic molecules significantly affecting liver cancer immunotherapySemantic proximity Read

An immunogenic cell death-associated gene signature predicts prognosis in hepatocellular carcinomaSemantic proximity Read

Identification of Prognostic Gene Signature Associated with Tumor Microenvironment of CholangiocarcinomaSemantic proximity Read

Identification of secretory protein related Biomarkers for Primary Biliary Cholangitis based on Machine Learning and experimental validationSemantic proximity Read

A model based on Immunogenic cell death-related genes can predict prognosis and drug sensitivity in patients with hepatocellular carcinomaSemantic proximity Read

MMP14 is a diagnostic gene of intrahepatic cholangiocarcinoma associated with immune cell infiltrationSemantic proximity Read

Development and validation of a robust immune-related risk signature for hepatocellular carcinomaSemantic proximity Read

A Novel Immune‑Related Gene-Based Model: Prognosis and Immunotherapy Response in Hepatocellular CarcinomaSemantic proximity Read

Establishment of a prognostic model of hepatocellular carcinoma based on inflammatory factor-related genes and prognosis-related characteristicsSemantic proximity Read

ldentify potential feature genes and immune cell infiltration of HIRI based on branched-chain amino acid-related genes by machine learning and experimental validationSemantic proximity Read