Article

Cerebrospinal Fluid Chloride as an Independent Prognostic Biomarker in Cryptococcal Meningitis: A Dual-Center Externally Validated Machine Learning Study with SHAP-Based Interpretability

2026-08-14

Abstract excerpt

<title>Abstract</title> <p>Background Cryptococcal meningitis (CM) carries a high 10-week mortality rate, necessitating accurate early prognostic tools. While cerebrospinal fluid chloride (CSF-Cl) is a routine test, its independent prognostic value in CM remains ill-defined. Furthermore, existing machine learning models lack external validation and clinical interpretability. This study aimed to validate CSF-Cl a...

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Literature Corpus work: 2d7f675b-0b39-5bae-8e15-0a929ff7682e
DOI: 10.21203/rs.3.rs-10261941/v1

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Cerebrospinal Fluid Chloride as an Independent Prognostic Biomarker in Cryptococcal Meningitis: A Dual-Center Externally Validated Machine Learning Study with SHAP-Based InterpretabilityDOI 10.21203/rs.3.rs-10261941/v1Read

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