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Assessing Genetic Causality of Periodontal Disease and Atrial Fibrillation by Potential Mediators: A Two-Step Mediating Mendelian Randomization Study

2024-02-02

Abstract excerpt

<title>Abstract</title> <p>Background The independent causality of periodontal disease on atrial fibrillation (AF) and the modifiable risk factors mediating the pathogenesis remain unclear. Method First, to confirm the independent causality, this study underwent the bidirectional and multivariable Mendelian Randomization (MR) underlying the genome-wide association studies (GWAS) of periodontal disease (87497 ca...

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Literature Corpus work
28818c11-b48d-5619-ab3e-d7b96eca32fc
DOI
10.21203/rs.3.rs-3881463/v1
Open publication

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