Article

Simultaneous Genomic and Metagenomic Analysis for Miscarriage and Stillbirth Further Increases the Diagnostic Utility of Genome Sequencing

2022-02-21

Abstract excerpt

<title>Abstract</title> <p>Congenital abnormalities and infections are the predominant cause of perinatal death in developed countries. While standard-of-care autopsy investigations can ascertain the event that caused the death, the aetiology cannot always be established. Genetic approaches have demonstrated utility in identifying the underlying causes of congenital anomalies and infectious diseases, but the feas...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 283bb7a0-5458-5a38-8d6c-51633556b5c0
DOI: 10.21203/rs.3.rs-1366032/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Simultaneous Genomic and Metagenomic Analysis for Miscarriage and Stillbirth Further Increases the Diagnostic Utility of Genome SequencingDOI 10.21203/rs.3.rs-1366032/v1Read

Metagenomic Next-Generation Sequencing for the Diagnosis of Neonatal Infectious DiseasesSemantic proximity Read

Metagenomic sequencing of post-mortem tissue samples for the identification of pathogens associated with neonatal deathsSemantic proximity Read

An approach to determining the most common causes of stillbirth in low and middle-income countries: A commentarySemantic proximity Read

Potential for diagnosis of infectious disease from the 100,000 Genomes Project Metagenomic Dataset: Recommendations for reporting resultsSemantic proximity Read

The Human Intolerome: a curated database to prioritize genomic variants in stillbirth, pregnancy loss, and neonatal deathSemantic proximity Read

A genomic autopsy identifies causes of perinatal death and provides options to prevent recurrenceSemantic proximity Read

Singleton rapid long-read genome sequencing as first tier genetic test for critically Ill children with suspected genetic diseasesSemantic proximity Read

Pregnancy-Associated Lung Abscess from a Migratory Childhood Foreign Body: A Case Report and Literature ReviewSemantic proximity Read

Comprehensive human amniotic fluid metagenomics supports the sterile womb hypothesisSemantic proximity Read

Rapid Whole Genome Sequencing in Critically Ill Neonates Enables Precision Medicine PipelineSemantic proximity Read

Clinically relevant DNA viruses in pregnancySemantic proximity Read

Genomic and Machine Learning Approaches for Predicting Gut-Microbe Infections in Preterm Infants: A Systematic Review of African StudiesSemantic proximity Read